ES417807A1 - Procedimiento para la obtencion de 2-alquilamino-dehidropi-rinas. - Google Patents
Procedimiento para la obtencion de 2-alquilamino-dehidropi-rinas.Info
- Publication number
- ES417807A1 ES417807A1 ES417807A ES417807A ES417807A1 ES 417807 A1 ES417807 A1 ES 417807A1 ES 417807 A ES417807 A ES 417807A ES 417807 A ES417807 A ES 417807A ES 417807 A1 ES417807 A1 ES 417807A1
- Authority
- ES
- Spain
- Prior art keywords
- phenyl
- substituted
- lower alkyl
- amino
- dihydropyridine derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- SWBVHDUHZQMKEK-UHFFFAOYSA-N 3,4-dihydropyridin-6-amine Chemical class NC1=CCCC=N1 SWBVHDUHZQMKEK-UHFFFAOYSA-N 0.000 title 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- WHGZPSATAVMLQM-UHFFFAOYSA-N 3,3-diaminoprop-2-enoic acid Chemical class NC(N)=CC(O)=O WHGZPSATAVMLQM-UHFFFAOYSA-N 0.000 abstract 1
- RDOAUPPSCNSYPM-UHFFFAOYSA-N 3,4-dihydropyridine Chemical group C1CC=NC=C1 RDOAUPPSCNSYPM-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 229940030600 antihypertensive agent Drugs 0.000 abstract 1
- 239000002220 antihypertensive agent Substances 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- 210000004351 coronary vessel Anatomy 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pulmonology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2239815A DE2239815C2 (de) | 1972-08-12 | 1972-08-12 | 2-Alkylamino-dihydropyridine, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES417807A1 true ES417807A1 (es) | 1976-03-01 |
Family
ID=5853453
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES417807A Expired ES417807A1 (es) | 1972-08-12 | 1973-08-11 | Procedimiento para la obtencion de 2-alquilamino-dehidropi-rinas. |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US3959292A (en]) |
| JP (1) | JPS5626660B2 (en]) |
| KR (1) | KR780000072B1 (en]) |
| AT (1) | AT327194B (en]) |
| AU (1) | AU469267B2 (en]) |
| BE (1) | BE803474A (en]) |
| BG (1) | BG22816A3 (en]) |
| CA (1) | CA1016945A (en]) |
| CH (1) | CH583196A5 (en]) |
| CS (1) | CS178892B2 (en]) |
| DD (1) | DD109627A5 (en]) |
| DE (1) | DE2239815C2 (en]) |
| DK (1) | DK136062C (en]) |
| ES (1) | ES417807A1 (en]) |
| FI (1) | FI55998C (en]) |
| FR (1) | FR2195450B1 (en]) |
| GB (1) | GB1384219A (en]) |
| HU (1) | HU167991B (en]) |
| IE (1) | IE37989B1 (en]) |
| IL (1) | IL42933A (en]) |
| LU (1) | LU68206A1 (en]) |
| NL (1) | NL7311031A (en]) |
| NO (1) | NO139130C (en]) |
| PL (1) | PL89396B1 (en]) |
| RO (1) | RO62914A (en]) |
| SE (1) | SE386164B (en]) |
| SU (1) | SU475772A3 (en]) |
| YU (1) | YU36172B (en]) |
| ZA (1) | ZA735460B (en]) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2639257A1 (de) * | 1976-09-01 | 1978-03-02 | Bayer Ag | Aminoalkylidenamino-1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| US4442100A (en) * | 1979-12-11 | 1984-04-10 | Bayer Aktiengesellschaft | Substituted 2-amino-3,4-dihydropyridine derivatives, their production and their medicinal use |
| DE3134945A1 (de) * | 1981-09-03 | 1983-03-17 | Bayer Ag, 5090 Leverkusen | Substituierte 2-amino-3,4-dihydropyridinderivate, verfahren zu ihrer herstellung und ihre verwendung in arzneimittel |
| ATE50987T1 (de) * | 1982-05-10 | 1990-03-15 | Takeda Chemical Industries Ltd | Dihydropyridinderivate, deren herstellung und verwendung. |
| US4603135A (en) * | 1983-10-17 | 1986-07-29 | Takeda Chemical Industries, Ltd. | Substituted piperazinyl alkyl esters of 2-amino-4-aryl-1,4-dihydro-6-alkyl-3,5-pyridinedicarboxylates |
| US4678796A (en) * | 1984-11-30 | 1987-07-07 | Warner-Lambert Company | 2-alkylidene derivatives of 1,2,3,4-tetrahydropyridine-2,5-pyridine carboxylic acid dialkyl esters useful for treatment of cardiovascular disorders |
| CA1267416A (en) | 1985-06-17 | 1990-04-03 | Ila Sircar | 1,4-dihydropyridine derivatives useful for the treatment of cardiovascular disorders |
| US4732898A (en) * | 1986-04-29 | 1988-03-22 | Warner-Lambert Company | 2-(2-aryl-2-oxoalkylidene) analogs of-3,5-pyridinedicarboxylic acid dialkyl esters useful for treatment of cardiovascular disorders |
| EP3730264B1 (en) | 2017-12-22 | 2022-08-24 | Toray Industries, Inc. | Tape-shaped prepreg and production method therefor |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3441648A (en) * | 1967-02-07 | 1969-04-29 | Smithkline Corp | Compositions and methods for lowering blood pressure with 1,4-dihydropyridines |
| DE1670827C3 (de) * | 1967-03-20 | 1974-10-24 | Bayer Ag, 5090 Leverkusen | 4-(2'-Nitrophenyl)-2,6-dimethyl-3,5-dicarbmethoxy-1,4-dihydropyridin |
| DE1670824C3 (de) * | 1967-03-20 | 1978-08-03 | Bayer Ag, 5090 Leverkusen | 1,4-Dihydropyridin-33-dicarbonsäurealkylester |
| DE1923990C3 (de) * | 1969-05-10 | 1978-11-23 | Bayer Ag | Verfahren zur Herstellung von N-substituierten M-Dihydropyridin-S.S-dicarbonsäureestern |
| DE2013431C3 (de) * | 1970-03-20 | 1979-12-20 | Bayer Ag, 5090 Leverkusen | 4-Azidophenyl-l,4-dihydropyridin-3,5-dicarbonsäureester |
-
1972
- 1972-08-12 DE DE2239815A patent/DE2239815C2/de not_active Expired
-
1973
- 1973-07-30 US US05/383,962 patent/US3959292A/en not_active Expired - Lifetime
- 1973-08-02 CA CA177,996A patent/CA1016945A/en not_active Expired
- 1973-08-06 YU YU2133/73A patent/YU36172B/xx unknown
- 1973-08-07 RO RO7300075742A patent/RO62914A/ro unknown
- 1973-08-08 PL PL1973164560A patent/PL89396B1/pl unknown
- 1973-08-08 SU SU1955736A patent/SU475772A3/ru active
- 1973-08-08 BG BG024292A patent/BG22816A3/xx unknown
- 1973-08-09 NL NL7311031A patent/NL7311031A/xx not_active Application Discontinuation
- 1973-08-09 IL IL42933A patent/IL42933A/en unknown
- 1973-08-09 SE SE7310938A patent/SE386164B/xx unknown
- 1973-08-10 DK DK442673A patent/DK136062C/da not_active IP Right Cessation
- 1973-08-10 BE BE134458A patent/BE803474A/xx not_active IP Right Cessation
- 1973-08-10 IE IE1374/73A patent/IE37989B1/xx unknown
- 1973-08-10 FR FR7329380A patent/FR2195450B1/fr not_active Expired
- 1973-08-10 AU AU59124/73A patent/AU469267B2/en not_active Expired
- 1973-08-10 FI FI2517/73A patent/FI55998C/fi active
- 1973-08-10 CH CH1160673A patent/CH583196A5/xx not_active IP Right Cessation
- 1973-08-10 JP JP8935573A patent/JPS5626660B2/ja not_active Expired
- 1973-08-10 CS CS7300005659A patent/CS178892B2/cs unknown
- 1973-08-10 NO NO3196/73A patent/NO139130C/no unknown
- 1973-08-10 LU LU68206A patent/LU68206A1/xx unknown
- 1973-08-10 DD DD172832A patent/DD109627A5/xx unknown
- 1973-08-10 ZA ZA735460A patent/ZA735460B/xx unknown
- 1973-08-10 GB GB3795073A patent/GB1384219A/en not_active Expired
- 1973-08-10 HU HUBA2965A patent/HU167991B/hu unknown
- 1973-08-11 ES ES417807A patent/ES417807A1/es not_active Expired
- 1973-08-13 AT AT707073A patent/AT327194B/de not_active IP Right Cessation
- 1973-08-13 KR KR7301318A patent/KR780000072B1/ko not_active Expired
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